I've been using a technique that uses the brushes at full opacity. It's been scary to work with colors in that bold of a fashion, but I'm really liking the results. Even better is that the process is so much quicker this way. I'll be using this technique more often from now on.
This one was inspired by a scene from Breaking Bad with one of it's craziest and most wild characters Tuco Salamanca.
https://youtu.be/njtfNPB-YKg?t=120
Breaking Bad was such a great show.